Research

Research at the Center for Drug Design covers a broad spectrum of diseases and treatment methods. CDD programs are periodically reviewed by the Scientific Advisory Committee.

Topic	Center Members	Focus
Antibiotics	Robert Vince	Vancomycin and penicillin derivatives
Antibiotics	Courtney Aldrich	Vancomycin derivatives
	Krzysztof W. Pankiewicz	Drug-resistant tuberculosis
	Steve Patterson	Blocking cell wall synthesis

Cancer	Robert Vince	General anticancer agents
Cancer	Stephen S. Hecht	Behavior and detoxification of carcinogens in the body
	Thomas R. Hoye	Natural products and angiogenesis
	Krzysztof W. Pankiewicz	Chronic myelogenous leukemia
	Steve Patterson	Cellular differentiation
	Thomas Shier	Carcinogenic effects of mycotoxins, aflatoxins, and fumonisins

Gene Therapy	Thomas Shier	Non-viral gene delivery methods
Gene Therapy

Neurological Disorders	Herbert Nagasawa	Parkinson's Disease and delivery of drugs to the brain
Neurological Disorders	Paul Tuite	Parkinson's Disease and other movement disorders
	George L. Wilcox	Neurotransmission of pain

Pesticides	Thomas Shier	Activity of betulin from birch bark
Pesticides

Toxins	David Ferguson	Detoxification of halogenated hydrocarbons
Toxins

Viral Diseases	Robert Vince	HIV, Herpes, Hepatitis B and C
Viral Diseases	David Ferguson	HIV, Herpes
	Louis M. Mansky	Replication of human retroviruses
	Krzysztof W. Pankiewicz	West Nile virus and other RNA viruses

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