Seminar Schedule

2009

Jun 17: Matthew Brenner, MD, Department of Medicine - Pulmonary and Critical Care, University of California - Irvine
10:30 AM, in 2-690 Moos Tower
Topic: Diffuse Optical Spectroscopy Assessment of Cyanide Poisoning and Treatment in an Animal Mode.

May 20: Yves Pommier, MD Ph D, Laboratory of Molecular Pharmacology, National Cancer Institute
10:30 AM, in 2-520 Moos Tower
Topic: HIV Integrase Inhibitors

Apr 15: Ingo Muegge, Ph D, Boehringer Ingelheim Parmaceuticals, Ridgefield, CT
10:30 AM, in 2-520 Moos Tower
Topic: De Novo Design of Drug-Like Molecules.

Mar 18: Michael Jung, Ph D, Department of Chemistry and Biochemistry, UCLA
10:30 AM, in 2-520 Moos Tower (Canceled)
Topic: Rational Drug Design for the Treatment of Hormone Refractory Prostate Cancer.

Feb 18: Yinduo Ji, Ph D, Department of Veterinary and Biomedical Sciences, University of Minnesota
10:30 AM, in 2-520 Moos Tower
Topic: Regulated Antisense RNA in Anti-Infective Drug Discovery.

Jan 21: Kevin Reynolds, Ph D, Department of Chemistry, Portland State University
10:30 AM, in 2-520 Moos Tower
Topic: It ALL Starts with abH-Fatty Acid and Prodiginie Biosynthesis.

2008

Dec 17: Michael Staake, Ph D, Center for Drug Design, University of Minnesota
10:30 AM, in 5-125 Moos Tower
Topic: Phosphonoxins: Novel Phosphonate Analogs of Antifungal Polyxins.

Nov 19: David Newman, D Phil, Natural Products Branch, National Cancer Institute
10:30 AM, in 1-451 Moos Tower
Topic: Wanderings with Nature: Mother Nature and Natural Product.

Oct 15: Pradipsinh Rathod Ph D, Department of Chemistry, University of Washington
10:30 AM, in 1-451 Moos Tower
Topic: New Antimetabolites Against Malaria.

Sep 17: Bradley Smith Ph D, Department of Chemistry and Biochemistry, University of Notre Dame
10:30 AM, in 2-620 Moos Tower
Topic: The Promise and Practice of Molecular Imaging in Drug Discovery.

May 28: John Blanchard, Ph D, Department of Biochemistry, Albert Einstein College of Medicine
10:30 AM, in 5-125 Moos Tower
Topic: Tubercolosis: One Big Problem; Two Little Stories.

May 21: Matthew Brenner, MD, Department of Medicine - Pulmonary and Critical Care, University of California - Irvine
10:30 AM, (Canceled)
Topic: Diffuse Optical Spectroscopy Assessment of Cyanide Poisoning and Treatment in an Animal Mode.

May 7: Nikunj Somia, PhD, Department of Genetics, Cell Biology and Development, University of Minnesota
10:30 AM, in 2-580 Moos Tower
Topic: Gene Discovery Using Retroviral Vectors: From Cancer to HIV.

Apr 16: Mark Walter, PhD, Department of Microbiology and Structural Biology, University of Alabama
10:30 AM, in 2-650 Moos Tower
Topic: Structural Analysis of Cytokine Receptor Interactions to Aid Drug Discovery.

Mar 19: Suzanne Walker, Ph D, Department of Chemistry and Biochemistry, Harvard
10:30 AM, in 5-125 Moos Tower
Topic: Glycosyltransferase Inhibitros.

2007

Dec 19: Chengguo Xing, PhD, Department of Medicinal Chemistry, University of Minnesota
10:30 AM, in 1-450 Moos Tower
Topic: Studies of HA 14-1 - Can we selectively target ER-specific Bcl-2 protein?

Nov 14: Gerry Boss, MD, Department of Medicine, UCSD
10:30 AM, in 2-530 Moos Tower
Topic: Of Fire, Bugs, and Terrorists: The Many Faces of Cyanide.

Oct 17: Carole Bewley, PhD, Laboratory of Bioorganic Chemistry, NIH
10:45 AM, in 2-530 Moos Tower
Topic: Structural studies of HIV-1 coreceptors and inhibitors.

Sep 19: Vern L. Schramm, PhD, Department of Biochemistry, Albert Einstein College of Medicine, Yeshiva University
10:30 AM, in 2-530 Moos Tower
Topic: Enzymatic Transition States and Inhibitor Design.

Apr 18: Nouri Neamati, PhD, Department of Pharmacology and Pharmaceutical Sciences, University of Southern California
10:30 AM, in 5-125 Moos Tower
Topic: Design and discovery of second-generation HIV-1 integrase inhibitors.

Mar 21: Anthony Pegg, PhD, Department of Cellular and Molecular Physiology, Penn State Milton S. Hershey Medical Center
3:30 PM, in 1-450G Moos Tower
Topic: Inactivation of DNA Repair Alkyltransferase by Pseudosubstrates.

Feb 21: Allen Reitz, PhD, RW Johnson PRI
3:30 PM, in 5-125 Moos Tower
Topic: BACE Inhibitors for the Treatment of Alzheimer's Disease.

Jan 17: Clifton E. Barry III, PhD, National Institutes of Health
1:30 PM, in 2-520 WDH
Topic: Strategies for target selection and lead optimization to improve tuberculosis chemotherapy. 

2006

Nov 15: Alexander Wlodawer, PhD, National Institutes of Health
4:00 PM, in 2-520 WDH
Topic: How to turn the sweet tooth of viruses into their Achilles' heel by utilizing antiviral lectins.

Oct 18: Mano Manoharan, Alnylam Pharmaceuticals
4:00 PM, in 2-520 WDH
Topic: Silence as Therapy: RNA interference using chemically modified siRNAs.

June 21: Shahriar Mobashery, PhD, Department of Chemistry and Biochemistry, Notre Dame
1:30 PM, in 4-180 WDH
Topic: Emergence of Staphylococcus aureus as a Clinical Scourge.

May 17: Marvin Miller, PhD, Department of Chemistry and Biochemistry, Notre Dame
1:30 PM, in 4-180 WDH
Topic: Acylnitroso Cycloaddition Chemistry: Applications to the Design, Syntheses and Studies of Bioactive Compounds.

April 19: Steven Ealick, PhD, Department of Chemistry and Chemical Biology, Cornell University
10:30 AM, in 4-180 WDH
Topic: Structural Evidence for Evolution of the Purine Biosynthetic Pathway.

Apr 12: Waldemar Priebe, PhD, MD Anderson Cancer Center, University of Texas
11:30 AM in 2-520 Moos Tower.
Topic: The Discovery and Development of Blood-Brain Barrier (BBB) Penetrating Anthracyclines for the Treatment of Brain Tumors.

Mar 15: Boris Striepen, PhD, University of Georgia
1:30 PM in 2-520 Moos Tower
Topic: Transferred Organelles and Pathways as Drug Targets in Protozoan Parasites.

Feb 15: William F. Prout, PhD, IPLM Group, P.A.
1:30 PM in 4-180 WDH.
Topic: Patent Strategies and Techniques - A Guide for University Professionals.

Jan 18: Shana Sturla, PhD, Department of Medicinal Chemistry, University of Minnesota
1:30 PM in 4-180 Weaver-Densford Hall
Topic: Acylfulvenes: Reductive Bioactivation and Antitumor Actitivy.

2005

Nov 16: Anton Hopfinger, PhD, College of Pharmacy, University of Illinois (Chicago)
1:30 PM in 2-520 Moos Tower
Topic: Design of Glycogen Phosphorylase Inhibitors: An Example of Turn-Key Preclinical Drug Discovery.

Oct 27: Pei-Yong Shi, PhD, New York State Department of Health
9:30 AM in 4-180 Weaver-Densford Hall
Topic: Flavivirus Replication and Antiviral Drug Discovery.

Jul 19: Shiv Kumar, PhD, G.E. Healthcare/Amersham Biosciences
10:30 AM in 7-193/195 WDH
Topic: Nucleotide Chemistry & Biotechnology Applications.

May 4: Robert K. Roth, MS JD, Miller Canfield PL
1:30 PM in 7-193/195 WDH
Topic: Protecting Your Interests: Patent Law and Research.

Feb 21: Lizbeth Hedstrom, PhD, Brandeis University
10:30 AM in 2-580 Moos Tower
Topic: IMP Dehydrogenase and the Dynamics of Drug Selectivity.

Jan 10: Dr. Leo Beigelman, Transgenomic, Inc
9:15 AM in 7-193/195 WDH
Topic: Medicinal Chemistry of RNA-based Therapeutics.

2004

Nov. 30: Prof. Peter Tonge, SUNY-Stonybrook
10:15 AM in 7-193/195 WDH
Topic: Mycolic acids, Menaquinone and Mycobactin: Tuberculosis Drug Discovery Beyond the Magic Mountain.

Nov. 15: Dr. Dan Cook, Carlsbad Pharmaceuticals
11:00 AM in 7-193/195 WDH
Topic: Novel Anti-HIV Agents: Nucleoside Triphosphate Mimics (N3PMs) and their Prodrugs (N3PM-PDs).