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Seminar Schedule

2008

Dec 17: Yves Pommier, MD Ph D, Laboratory of Molecular Pharmacology, National Cancer Institute

10:30 AM, TBA
Topic: TBA

 

Nov 19: David Newman, D Phil, Natural Products Branch, National Cancer Institute

10:30 AM, TBA
Topic: Wanderings with Nature: Mother Nature and Natural Products

 

Oct 15: Pradipsinh Rathod Ph D, Department of Chemistry, University of Washington

10:30 AM, TBA
Topic: New Antimetabolites Against Malaria

 

Sep 17: Bradley Smith Ph D, Department of Chemistry and Biochemistry, University of Notre Dame

10:30 AM, TBA
Topic: The Promise and Practice of Molecular Imaging in Drug Discovery

 

May 28: John Blanchard, Ph D, Department of Biochemistry, Albert Einstein College of Medicine

10:30 AM, in 5-125 Moos Tower
Topic: Tubercolosis: One Big Problem; Two Little Stories

 

May 21: Matthew Brenner, MD, Department of Medicine - Pulmonary and Critical Care, University of California - Irvine

10:30 AM, in 5-125 Moos Tower
Topic: Diffuse Optical Spectroscopy Assessment of Cyanide Poisoning and Treatment in an Animal Mode

 

May 7: Nikunj Somia, PhD, Department of Genetics, Cell Biology and Development, University of Minnesota

10:30 AM, in 2-580 Moos Tower
Topic: Gene Discovery Using Retroviral Vectors: From Cancer to HIV

 

Apr 16: Mark Walter, PhD, Department of Microbiology and Structural Biology, University of Alabama

10:30 AM, in 2-650 Moos Tower
Topic: Structural Analysis of Cytokine Receptor Interactions to Aid Drug Discovery

 

Mar 19: Suzanne Walker, Ph D, Department of Chemistry and Biochemistry, Harvard

10:30 AM, in 5-125 Moos Tower
Topic: Glycosyltransferase Inhibitros

 

2007

Dec 19: Chengguo Xing, PhD, Department of Medicinal Chemistry, University of Minnesota

10:30 AM, in 1-450 Moos Tower
Topic: Studies of HA 14-1 - Can we selectively target ER-specific Bcl-2 protein?

 

Nov 14: Gerry Boss, MD, Department of Medicine, UCSD

10:30 AM, in 2-530 Moos Tower
Topic: Of Fire, Bugs, and Terrorists: The Many Faces of Cyanide

 

Oct 17: Carole Bewley, PhD, Laboratory of Bioorganic Chemistry, NIH

10:45 AM, in 2-530 Moos Tower
Topic: Structural studies of HIV-1 coreceptors and inhibitors

 

Sep 19: Vern L. Schramm, PhD, Department of Biochemistry, Albert Einstein College of Medicine, Yeshiva University

10:30 AM, in 2-530 Moos Tower
Topic: Enzymatic Transition States and Inhibitor Design

 

Apr 18: Nouri Neamati, PhD, Department of Pharmacology and Pharmaceutical Sciences, University of Southern California

10:30 AM, in 5-125 Moos Tower
Topic: Design and discovery of second-generation HIV-1 integrase inhibitors

 

Mar 21: Anthony Pegg, PhD, Department of Cellular and Molecular Physiology, Penn State Milton S. Hershey Medical Center

3:30 PM, in 1-450G Moos Tower
Topic: Inactivation of DNA Repair Alkyltransferase by Pseudosubstrates

 

Feb 21: Allen Reitz, PhD, RW Johnson PRI

3:30 PM, in 5-125 Moos Tower
Topic: BACE Inhibitors for the Treatment of Alzheimer's Disease

 

Jan 17: Clifton E. Barry III, PhD, National Institutes of Health

1:30 PM, in 2-520 WDH
Topic: Strategies for target selection and lead optimization to improve tuberculosis chemotherapy. 

 

2006

Nov 15: Alexander Wlodawer, PhD, National Institutes of Health

4:00 PM, in 2-520 WDH
Topic: How to turn the sweet tooth of viruses into their Achilles' heel by utilizing antiviral lectins.

 

Oct 18: Mano Manoharan, Alnylam Pharmaceuticals

4:00 PM, in 2-520 WDH
Topic: Silence as Therapy: RNA interference using chemically modified siRNAs

 

June 21: Shahriar Mobashery, PhD, Department of Chemistry and Biochemistry, Notre Dame

1:30 PM, in 4-180 WDH
Topic: Emergence of Staphylococcus aureus as a Clinical Scourge

 

May 17: Marvin Miller, PhD, Department of Chemistry and Biochemistry, Notre Dame

1:30 PM, in 4-180 WDH
Topic: Acylnitroso Cycloaddition Chemistry: Applications to the Design, Syntheses and Studies of Bioactive Compounds

 

April 19: Steven Ealick, PhD, Department of Chemistry and Chemical Biology, Cornell University

10:30 AM, in 4-180 WDH
Topic: Structural Evidence for Evolution of the Purine Biosynthetic Pathway

 

Apr 12: Waldemar Priebe, PhD, MD Anderson Cancer Center, University of Texas

11:30 AM in 2-520 Moos Tower.
Topic: The Discovery and Development of Blood-Brain Barrier (BBB) Penetrating Anthracyclines for the Treatment of Brain Tumors.

 

Mar 15: Boris Striepen, PhD, University of Georgia

1:30 PM in 2-520 Moos Tower.
Topic: Transferred Organelles and Pathways as Drug Targets in Protozoan Parasites.

 

Feb 15: William F. Prout, PhD, IPLM Group, P.A.

1:30 PM in 4-180 WDH.
Topic: Patent Strategies and Techniques - A Guide for University Professionals.

 

Jan 18: Shana Sturla, PhD, Department of Medicinal Chemistry, University of Minnesota

1:30 PM in 4-180 Weaver-Densford Hall
Topic: Acylfulvenes: Reductive Bioactivation and Antitumor Actitivy. 

 

2005

Nov 16: Anton Hopfinger, PhD, College of Pharmacy, University of Illinois (Chicago)

1:30 PM in 2-520 Moos Tower
Topic: Design of Glycogen Phosphorylase Inhibitors: An Example of Turn-Key Preclinical Drug Discovery.

 

Oct 27: Pei-Yong Shi, PhD, New York State Department of Health

9:30 AM in 4-180 Weaver-Densford Hall
Topic: Flavivirus Replication and Antiviral Drug Discovery.

 

Jul 19: Shiv Kumar, PhD, G.E. Healthcare/Amersham Biosciences

10:30 AM in 7-193/195 WDH
Topic: Nucleotide Chemistry & Biotechnology Applications.

 

May 4: Robert K. Roth, MS JD, Miller Canfield PL

1:30 PM in 7-193/195 WDH
Topic: Protecting Your Interests: Patent Law and Research.

 

Feb 21: Lizbeth Hedstrom, PhD, Brandeis University

10:30 AM in 2-580 Moos Tower
Topic: IMP Dehydrogenase and the Dynamics of Drug Selectivity.

 

Jan 10: Dr. Leo Beigelman, Transgenomic, Inc.

9:15 AM in 7-193/195 WDH
Topic: Medicinal Chemistry of RNA-based Therapeutics. 

 

2004

Nov. 30: Prof. Peter Tonge, SUNY-Stonybrook

10:15 AM in 7-193/195 WDH
Topic: Mycolic acids, Menaquinone and Mycobactin: Tuberculosis Drug Discovery Beyond the Magic Mountain.

 

Nov. 15: Dr. Dan Cook, Carlsbad Pharmaceuticals

11:00 AM in 7-193/195 WDH
Topic: Novel Anti-HIV Agents: Nucleoside Triphosphate Mimics (N3PMs) and their Prodrugs (N3PM-PDs).


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